Nia’s story  

I have always wanted to tell Nia’s story, but up to this point, I’ve been far too emotional to do so. It is early Sunday morning, and Nia just walked over to our bed, cuddling alongside us and falling asleep again. Looking at her, sleeping soundly and happily, fills me with pride and enormous happiness and that I am finally waking up from a nightmare that started nearly a year ago…  

Nia was one day short of 10 months old on Tuesday, April 17th, 2001 . My husband John and I took Nia to visit my parents in Germany for a few days over the Easter holidays. I had booked a routine check-up with a German paediatrician during our stay because I was not happy with Nia’s eating habits, her low weight gain, and her lack of mobility development, (she still did not roll over onto her tummy or sit up by herself). She also just recovered from bronchiolitis. I did not have much trust in the UK ’s NHS system—the health visitors kept telling us that Nia ate as much as she needs, and since John and I were quite slim children, Nia was just the same. They explained her lack of movement was sheer laziness, and we should encourage her more to lie on her tummy. I always felt classified as the notorious first time Mum, which is a feeling I believe I share with most first time Mums. The German paediatrician, a female doctor, did all sorts of checks, and was generally content until she listened to Nia’s heart. The doctor closed her eyes and I saw her concentrating. I feared something was wrong. She then asked me if somebody already told me that Nia has a heart murmur (something that is quite common in babies and does not necessary mean that there is a problem). No, I said, nobody had mentioned it. She advised me to eventually get it checked by a paediatric cardiologist. I did not know how to get hold of one in the UK (we were planning to fly back two days later). The doctor kindly arranged for us to see the paediatric cardiologist in the regional hospital.  

Two hours later, my Mum, Nia, and I were in the hospital, waiting for the doctor to come (John had stayed back at my parents house since he was not interested in the shopping trip I have planned for the rest of the day). Nia had an ECG and an echocardiogram. The echo took more than an hour. The doctor did not say a word while poor little Nia screamed hysterically. It was the first time I have ever heard her scream in this way. I got more and more nervous, and after the longest hour in my life (up to that date) the doctor asked us to dress Nia and come down to his office. I then called John to come to the hospital, since I knew something must be terribly wrong. By the time we entered his office 10 minutes later, the doctor had already arranged for us to go to the heart unit of the children’s hospital in the city of Giessen (about 60 miles away). He suspected that Nia had a rare heart condition called ALCAPA (Anomalous origin of the Left Coronary Artery from the Pulmonary Artery). With this condition, the left side of a baby’s heart muscle doesn’t get the rich oxygen concentrated blood from the aorta, but the nearly oxygen-free blood out of the pulmonary artery. Therefore the heart muscle and the left side of the heart cannot function properly (it took me several months and a lot of studying to understand her condition). The doctor told us to drive directly to the children’s hospital, and not to drive by my parents’ house first to pack anything. It took us nearly two hours to get to Giessen . We were greeted by another paediatric cardiologist, Dr. Bauer. He did another series of tests and told us Nia was booked for a catheter examination the next day. That was the only way to see exactly what was wrong with her heart. He also added that if Nia indeed had ALCAPA, she would require open-heart surgery the following day. At that time, I luckily still had no clue of all the events to come.  

On Wednesday, April 18th, Nia’s 10 months birthday, we had to sign the consent form for the catheter examination. During the procedure, a tube is inserted  the flow of blood through in thetinto a vein in the thigh. The tube is pushed through her veins into her heart. A contrast fluid is fed through the tube and squirted into the heart. This fluid appears on x-rays, and enables the doctors to see the structure of the heart, the connections of cardiac veins and arteries, and the flow of blood through in the area. Sadly enough, the examination confirmed her condition, and later in the day, we had to sign the consent forms for the surgery the next day. Again, I was luckily still very unaware what open-heart surgery really meant—I was under the assumption that it must be nearly a routine operation by now, maybe slightly more risky then an appendectomy. To the contrary, we were told that the survival rate for open-heart surgeries is about 90 % (sounds high initially, but if you think that out of 100 babies, 10 die – it sound very scary).  

On Thursday, April 19th, at 7:30 am , nurses helped us roll Nia’s bed to the theatre. Nia was already drugged to go to sleep, but she stayed wide awake. She was pulling my hair, not wanting to let go. However, we had let go of her—we were not allowed to stay with her in the theatre. There is no way I can describe this feeling of totally losing control of my daughter, my life, and all of the things that are happening. For the next 5 hours, John and I walked around town, but every minute felt like hours. At noon , we walked up to the intensive care unit and after 30 minutes waiting, were at least told that she is out of the theatre and on her way up. At about 1:30 pm we were allowed to don green theatre gowns and ife, totally losee her. She was lying there, still knocked out from all the drugs, on the ventilator (the machine that does the breathing for her), with over a doze tubes going into or out of her. Strangely enough, this all did not scare me too much. I was just happy to see her and thinking she is the most beautiful little girl. I was hoping the worst was over then, but learned that the next 48 hours are indeed the critical ones. It took until Saturday for her situation to be called stabile. John and I spent most of the time waiting to get to see her in intensive care—we were usually only allowed to stay with her for short periods of time. This is very different from the UK , where parents are allowed to stay with their children for nearly most of the time. On Sunday she was taken off the ventilator and was again breathing on her own, waking up on and off. On Monday she was moved out of the intensive care unit onto the ward.  

Back on the ward, Nia was recovering, but also crying a lot. One of the nurses explained that Nia is “on cold turkey” – a condition drug addicts are on when they stop taking the drugs. Since Nia had been on morphine for nearly a week, her body had to adjust being without it. I slowly started to regain my confidence again, hoping this nightmare would be over soon. On Wednesday, April 25th, I met the head of Giessen ’s paediatric cardiologists, Professor Schranz. He told me that Nia’s condition was discovered very late (it is usually picked up in the first three months). Most babies with the condition untreated will not celebrate their first birthday, and when treated as late as Nia, very often need a heart transplant since the heart muscle is damaged and cannot be repaired. Nia apparently suffered from various heart attacks before (very often mistaken for colic – and Nia has been a very colicky infant) and her mitral valve (the valve between the left chambers of the heart) was seriously damaged and did not recover as expected after the surgery. In addition, the surgeon had not been able to perform the planned surgery, which had been to re-connect the left coronary artery to the aorta. Instead, he had to perform a bypass operation, very common in adults with coronary diseases. We were told that they had to do another catheter examination in a few weeks time to verify that the bypass is indeed functioning. On May 3rd, 2 weeks after her open-heart surgery, Nia underwent her second catheter exam. It showed that there was good blood flow in the bypass and that this would likely persist, but her mitral valve was still severely leaking and could require further surgery in the future. We flew back to the UK with several medications for Nia (8 times a day) and a referral to the Birmingham Children’s hospital (BCH).  

Nia had her first appointment at the BCH in June. The consultant there, Dr. Stuemper (also German), doubted that the bypass performed in Germany could indeed ensure enough blood flow to the left heart muscle. He suggested doing another catheter exam later in the year to see how the bypass developed. We saw him again in July and then were scheduled to come back in October. In September, I had to go on a business trip to Germany . I took Nia along to have her checked again in Giessen , were she had her first surgery. Prof. Schranz he was still not happy with the mitral valve and urged us to get it repaired or replaced within the next three months. Strangely enough, he recommended that Nia have the surgery done at BCH since he considered Mr. Brawn, a paediatric cardiac surgeon there, one of the best in the world. Prof. Schranz promised to send a letter with his recommendation to BCH.  

At our next appointment with Dr. Stuemper in October, I expected to discuss the upcoming surgery. However, Dr. Stuemper did not concur with the German recommendation. He wanted to perform another catheter to see how the heart and bypass were doing. On December 4th Nia had her 3rd catheter done at BCH. Sadly, it confirmed Dr. Stuemper’s concern—the bypass was closed and did not supply the left side of the heart with blood. This explained the poor state of the mitral valve.  Dr. Stuemper strongly recommended another surgery for Nia using a technique called Takeuchi. This is a complex operation that is rarely performed and was classified as too dangerous from the consultant and surgeon in Germany (we were told by the German site that they have only seen fatalities with this type of surgery). But Dr. Stuemper was convinced this surgery would be Nia’s only change to save her heart and if we do not give it a go, Nia will need a heart transplant in the near future. A heart transplant might sound like a long-term fix, but sadly it is not—in babies with a successfully performed heart transplant, the survival rate is about 50 %, and the heart is expected to last for an average of 5 years before a new heart transplant is needed. Dr. Stuemper said he would try to book a surgery appointment with Mr. Brawn for two days later (December 6th). John and I were totally devastated, especially since we felt we were caught between two systems and not really knowing whom to trust. The next day, we were told to go home, since the surgery slot was taken away for an even more urgent case and we should expect to get an appointment in January. Dr. Stuemper said we should try to enjoy Christmas with daughter. A part of me feared that this decision was done because they have already given up on Nia and wanted us to at least celebrate Christmas together. Nearly 8 weeks of long waiting passed and we then got the appointment for Monday, January 28th 2002 . In the meantime, I contacted the Giessen hospital again. Prof. Schranz again urged us not to go ahead with the Takeuchi procedure, and only go for a mitral valve repair. He promised to discuss this with Dr. Stuemper, but never did. I do not know exactly why, but we decided to give our full trust to Birmingham . We met with Mr. Brawn, the surgeon, on the evening of January 27th. He is the most remarkable man I ever met – he sat down with us for more than an hour on that Sunday night. He told us that he did not know of any case where the Takeuchi procedure was done as a second attempt. Also, he said the Takeuchi procedure indeed is quite rarely used. He had only done a few (a decade prior) while working in Australia and did not know about the long-term outcome of these patients. Given his knowledge, sincerity, and honesty, John and I fully trusted him.  

Mr. Brawn saw us again the next morning together with Dr. Stuemper, who seemed extremely nervous. We signed the consent forms and at noon and carried Nia into the operation theatre. We were allowed to stay with her until she was asleep. Again, we had to let go of her, not knowing if and when we will see her again. After the first experience in Giessen , We were aware that we not only needed to wait for the surgery to finish, but also endure the following 48 hours after which she will hopefully be out of the danger zone. The surgery was estimated to last 6 hours, but one of the nurses must have misunderstood something and told us to check back again at 4 pm. At 4 pm , Nia was still in the theatre. John and I moved our bags into a room at the Edward House, next door to the hospital. The ward promised to ring us as soon as Nia came out of theatre, but by 6 pm I thought I would go nuts and had to go back to the ward. I literally ran into Mr. Brawn, who just came out of theatre to see us. Somehow he looked very sincere and I feared the worst – but for a change he had good news. The surgery was successful; he was even able to repair the mitral valve to a degree (something he doubted he would be able to do). He walked with us to Nia’s bedside in Intensive care (PICU). I was allowed to stay with her the whole time she was there. I never had to leave PICU, even when they took the ventilator out at 3am – only 9 hours after the surgery (last time it took 4 days). Seeing my baby on a ventilator, knowing she is not even breathing by herself and a slight mistake in medications or drugs could mean her end, is just pure horror. It was especially true since this second time, I was more aware of what can go wrong than I was the first time. But the staff members in PICU were just wonderful – they constantly kept me informed. As soon as Nia was taken off the ventilator, a nurse placed her in my arms, with all the rest of the tubes still attached. Nia then settled down (she was quite active, trying to pull her tubes out). She woke up early in the morning, and by the afternoon, she was transferred back to the ward – not even 24 hours after her surgery.  

Going back on the ward meant she was out of the critical phase. I had not eaten in nearly 24 hours and boy, was I hungry. I had a big breakfast, one of the best breakfasts I had had in several months. Everything went uphill from then on – she went through her “cold turkey” phase where she even pushed me away. On Monday, February 4th, Nia had to undergo her 4th catheter examination. Dr. Stuemper performed the catheter and saw us right after he left theatre. I will never forget the look on his face – he was so happy! Everything looked fine. Blood was flowing into the left coronary artery, and her mitral valve leakage was classified down to mild-moderate (before, it had been classified as severe). If he and I weren’t both stiff Germans, I truly would have kissed him! And then, even more amazingly, we were allowed to leave the next day, on Tuesday, February 5th.  

Today, Nia is still takes plenty of medication to help her heart recover. Nobody can predict how successful the long-term outcome of the surgery will be, or how the blood supply to the heart will establish in the long-term. But nobody who sees our little princess can believe what she has gone through. The only constant reminder is the big scar on her chest (looks like a big number “1” – how appropriate!). We were so lucky to live close to Birmingham , one of the leading paediatric heart units in the world. The care there was supreme. They absolutely fulfilled their promise that the parents are part of the team. We were constantly involved in Nia’s care; one of us was allowed to sleep next to her bedside; and every time a medical professional approached her, we were fully informed and could ask any questions. Dr. Stuemper and Mr. Brawn are more than my personal heroes, and I know there is nothing I can say or do to fully express my gratitude. Being so far away from our families in the US and Germany , John and I are also grateful for all the love and support we received from our colleagues and friends here in Milton Keynes . Without them, I doubt I would have stayed sane during the last year.  

I must apologize that this article got a lot longer than intended. I must stress that Nia’s condition is very rare, so I do not want to worry any of you.  ALCAPA occurs once in about 300,000 live births—so far, only 300 known cases world-wide. I just want to share one lesson with you that I have learned: always trust your instincts. Whenever you think something might not be right, say so.  

Enjoy every single day with your little ones—don’t worry too much about tomorrow, or be too upset about the past.  

Thank you,
Corinna